NUMEN is a project founded by Danish Council for Indepndent Research: Technology and Production, Ministry of High Education and Science (DFF-FTP– 4005-00482B).
Rapid detection of bacteria, virus, fungi or protozoa is the first step in protecting human health. However, available detection methods require hours to days. This project will develop electrochemical biosensors based on nucleic acids (NA), aptamers and antibodies (Ab) that convert the recognition of a microbe into a real-time detectable signal. This nanotechnology will be cost-effective, easy-to-handle, ultra-sensitive, and will allow rapid and simultaneous quantification of several different organisms. Biosensors exploiting target-probe NA hybridization or aptamer-ligand/Ab-antigen binding will be integrated within a multichannel microfluidic device and adapted to automatable sampling protocols, for use in environmental monitoring of drinking water supplies, recreational waters, and hospital and city air. Danish specialists from the microsensor-, pump- and measurement industry will participate in the development of the assay and the device prototype.
Elena Ferapontova Project Leader, iNANO, Aarhus University, Denmark
Ulrich Bay Gosewinkel Senior Researcher at Roskilde, Department of Environmental Science, Aarhus University, Denmark
Niels Bohse Hendriksen, Senior Researcher, Department of Environmental Science, Aarhus University, Denmark
Andreas Massling, Senior Researcher, Department of Environmental Science, Aarhus University, Denmark
Prof. Kevin W. Plaxco, Assoc. Director, Center for Bio-engineering, Uni. California, Santa Barbara, USA
Unisense A/S, World leading manufacturer of microsensors and instrumentation for microscale measurement, Aarhus, Denmark
GRUNDFOS Holding A/S, World's largest pump manufacturer, Bjerringbro, Denmark
TSI Inc (Danalytic ApS), World leading air-sampling company, Horsens, Denmark
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