Welcome to NUMEN:

Nanotechnologies for Ultrasensitive monitoring of Microbes in the human ENvironment

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Project description

NUMEN is a project founded by Danish Council for  Indepndent Research: Technology and Production, Ministry of High  Education and Science (DFF-FTP– 4005-00482B).
Rapid detection of  bacteria, virus, fungi or protozoa is the first step in protecting human  health. However, available detection methods require hours to days.  This project will develop electrochemical biosensors based on nucleic  acids (NA), aptamers and antibodies (Ab) that convert the recognition of  a microbe into a real-time detectable signal. This nanotechnology will  be cost-effective, easy-to-handle, ultra-sensitive, and will allow rapid  and simultaneous quantification of several different organisms.  Biosensors exploiting target-probe NA hybridization or  aptamer-ligand/Ab-antigen binding will be integrated within a  multichannel microfluidic device and adapted to automatable sampling  protocols, for use in environmental monitoring of drinking water  supplies, recreational waters, and hospital and city air. Danish  specialists from the microsensor-, pump- and measurement industry will  participate in the development of the assay and the device prototype. 


Project Team

Elena Ferapontova Project Leader, iNANO, Aarhus University, Denmark

Ulrich Bay Gosewinkel Senior Researcher at Roskilde,  Department of Environmental Science, Aarhus University, Denmark 

Niels Bohse Hendriksen, Senior Researcher, Department of Environmental Science, Aarhus University, Denmark   

Andreas Massling, Senior Researcher, Department of Environmental Science, Aarhus University, Denmark  

Prof. Kevin W. Plaxco,  Assoc. Director, Center for Bio-engineering, Uni. California, Santa Barbara, USA  

Unisense A/S,  World leading manufacturer of microsensors and instrumentation for microscale measurement, Aarhus, Denmark  

GRUNDFOS Holding A/S, World's largest pump manufacturer, Bjerringbro, Denmark  

TSI Inc (Danalytic ApS), World leading air-sampling company, Horsens, Denmark


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